Scientists have for the first time successfully delivered the gene-editing tool CRISPR into mouse brains and altered their behavior.
Rats with a mutation in CACNA1C, a gene linked to autism, make fewer happy squeaks while playing than controls do, and ignore other rats’ requests to play, a new study suggests.
Mice with a mutation in a top autism gene called SHANK3 have altered levels of certain gut bacteria, a new study shows.
People with mutations in SHANK3 have intellectual disability and other features of Phelan-McDermid syndrome, the condition most closely associated with this gene.
Girls with autism traits have fewer problems with social communication than boys do early on, but their skills worsen by adolescence, a new study suggests.
The brains of people with autism show a variety of structural differences from those of controls, according to a large imaging study.
Girls with an autism diagnosis have more severe impairments in social communication than boys with the diagnosis, according to a large population-based study.
Children with autism often have trouble understanding others’ thoughts, and some may compensate for this by creating scripts and using other learned strategies to navigate social si
Many women with traits of autism or attention deficit hyperactivity disorder (ADHD) report having been sexually abused as a child, according to a study of 4,500 people.
The bulk of the increase in autism prevalence the United States between 2000 and 2012 can be attributed to children on the mild end of the spectrum.
Epilepsy in infancy and the use of prescription medications during pregnancy are the strongest of 29 known risk factors for autism in a child, according to a large analysis of medical records.
Some children with autism carry rare mutations in DNA segments that flank genes and control their expression — and they tend to inherit these mutations from their unaffected fathers, accordin
An unusual brain response to sound may distinguish children with mutations in SCN2A, a leading candidate gene for autism.
Mice lacking CNTNAP2, a gene strongly linked to autism, are acutely sensitive to pain, according to a new study. Loss of the gene makes some of their sensory neurons unusually excitable.
The amygdala, a brain region that governs emotions, may contain an unusually high number of neurons in young children with autism.